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Stephen C Cunnane Selected Research

acetoacetic acid (acetoacetate)

7/2017Inverse relationship between brain glucose and ketone metabolism in adults during short-term moderate dietary ketosis: A dual tracer quantitative positron emission tomography study.
1/2016Can Ketones Help Rescue Brain Fuel Supply in Later Life? Implications for Cognitive Health during Aging and the Treatment of Alzheimer's Disease.
1/2015Lower brain 18F-fluorodeoxyglucose uptake but normal 11C-acetoacetate metabolism in mild Alzheimer's disease dementia.
11/2014[(11)C]-Acetoacetate PET imaging: a potential early marker for cardiac heart failure.
7/2008[11C] acetoacetate utilization by breast and prostate tumors: a PET and biodistribution study in mice.
7/2002Breath acetone is a reliable indicator of ketosis in adults consuming ketogenic meals.

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Stephen C Cunnane Research Topics

Disease

19Alzheimer Disease (Alzheimer's Disease)
05/2020 - 09/2006
17Cognitive Dysfunction
01/2022 - 09/2006
14Ketosis
12/2021 - 01/2002
9Insulin Resistance
01/2020 - 02/2008
6Seizures (Absence Seizure)
07/2015 - 01/2002
3Neurodegenerative Diseases (Neurodegenerative Disease)
05/2020 - 01/2017
3Drug Resistant Epilepsy
07/2015 - 01/2002
3Epilepsy (Aura)
07/2015 - 07/2002
3Atrophy
06/2014 - 08/2012
3Cardiovascular Diseases (Cardiovascular Disease)
01/2008 - 05/2002
2Prediabetic State (Prediabetes)
01/2020 - 01/2020
2Type 2 Diabetes Mellitus (MODY)
01/2020 - 06/2010
2Overweight
01/2015 - 05/2013
2Obesity
01/2015 - 09/2008
2Neoplasms (Cancer)
04/2009 - 07/2008
2Coronary Disease (Coronary Heart Disease)
04/2009 - 06/2008
2Myocardial Infarction
06/2008 - 01/2008
2Hypersensitivity (Allergy)
08/2004 - 12/2003
2Coronary Artery Disease (Coronary Atherosclerosis)
02/2003 - 08/2002
1Mitochondrial Diseases (Mitochondrial Disease)
01/2020
1Hypoglycemia (Reactive Hypoglycemia)
01/2016
1Left Ventricular Dysfunction
11/2015
1Weight Loss (Weight Reduction)
11/2015
1Glucose Intolerance
11/2015
1Dementia (Dementias)
01/2015
1Polycystic Ovary Syndrome (Syndrome, Stein-Leventhal)
01/2015
1Cardiotoxicity
11/2014
1Heart Failure
11/2014
1Heart Diseases (Heart Disease)
11/2014
1Cerebral Cortical Thinning
06/2014
1Prostatic Neoplasms (Prostate Cancer)
04/2014
1Alcoholism (Alcohol Abuse)
01/2013
1Liver Diseases (Liver Disease)
01/2013
1Chronic Disease (Chronic Diseases)
04/2009
1Nervous System Diseases (Neurological Disorders)
11/2008
1Hypertrophy
09/2008
1Hyperplasia
09/2008
1Sudden Death
06/2008
1Cardiac Arrhythmias (Arrythmia)
06/2008
1Inflammation (Inflammations)
02/2008

Drug/Important Bio-Agent (IBA)

22KetonesIBA
01/2022 - 01/2006
20Glucose (Dextrose)FDA LinkGeneric
01/2022 - 11/2008
11Fatty Acids (Saturated Fatty Acids)IBA
01/2020 - 09/2005
8Triglycerides (Triacylglycerol)IBA
12/2021 - 09/2005
7Docosahexaenoic AcidsIBA
01/2013 - 03/2004
6acetoacetic acid (acetoacetate)IBA
07/2017 - 07/2002
6Omega-3 Fatty Acids (Omega 3 Fatty Acids)IBA
02/2014 - 09/2006
4Apolipoprotein E4IBA
03/2017 - 10/2009
4alpha-Linolenic Acid (Linolenic Acid)IBA
01/2008 - 02/2003
3LipidsIBA
04/2009 - 04/2002
3Fish OilsIBA
06/2008 - 03/2007
3AcetoneIBA
01/2006 - 01/2002
2CarbohydratesIBA
01/2020 - 01/2002
2Biomarkers (Surrogate Marker)IBA
01/2020 - 01/2017
2Dietary Fats (Dietary Fat)IBA
11/2015 - 09/2008
2Phospholipids (Phosphatides)FDA LinkGeneric
04/2014 - 01/2012
2Apolipoproteins E (ApoE)IBA
02/2014 - 09/2013
2Nonesterified Fatty Acids (NEFA)IBA
01/2012 - 06/2010
2Unsaturated Fatty Acids (Polyunsaturated Fatty Acids)IBA
09/2008 - 09/2005
2Linoleic Acid (Linoleate)IBA
08/2007 - 02/2003
2CholesterolIBA
11/2004 - 01/2002
2SterolsIBA
11/2004 - 01/2002
2trans- 1,4- Bis(2- chlorobenzaminomethyl)cyclohexane DihydrochlorideIBA
11/2004 - 01/2002
1Vitamin B Complex (B Vitamins)IBA
01/2022
1RNA (Ribonucleic Acid)IBA
01/2020
1Hormones (Hormone)IBA
01/2020
1Dietary Carbohydrates (Carbohydrate, Dietary)IBA
01/2020
1ApolipoproteinsIBA
03/2017
1CarbonIBA
01/2016
1EstersIBA
01/2016
13-Hydroxybutyric Acid (beta-Hydroxybutyric Acid)IBA
01/2016
1Presenilin-1IBA
01/2016
1octanoic acid (caprylic acid)IBA
01/2016
1N-(gamma-aminobutyryl)glutamic acidIBA
07/2015
1gamma-Aminobutyric Acid (GABA)IBA
07/2015
1Neurotransmitter Agents (Neurotransmitter)IBA
07/2015
1Sucrose (Saccharose)IBA
03/2015
1Doxorubicin (Adriamycin)FDA LinkGeneric
11/2014
1Thyrotropin (Thyroid-Stimulating Hormone)FDA Link
09/2013
1Thyroid HormonesIBA
09/2013
1Thyroxine (Levothyroxine)FDA LinkGeneric
09/2013
1Triiodothyronine (Liothyronine)FDA LinkGeneric
09/2013
1AdiponectinIBA
05/2013
1Insulin (Novolin)FDA Link
05/2013
1C-Reactive ProteinIBA
05/2013
1Interleukin-6 (Interleukin 6)IBA
05/2013
1FructosamineIBA
05/2013
1Eicosapentaenoic AcidIBA
08/2012
1Omega-6 Fatty Acids (Omega 6 Fatty Acids)IBA
01/2012
1Oleic Acid (Oleate)IBA
01/2012
1Fluorodeoxyglucose F18 (Fludeoxyglucose F 18)FDA Link
03/2011
1PPAR alphaIBA
10/2009
1Acetates (Acetic Acid Esters)FDA Link
07/2008
1IsoprostanesIBA
02/2008
1Lipoprotein(a)IBA
02/2008
1oxidized low density lipoproteinIBA
02/2008

Therapy/Procedure

10Ketogenic Diet
01/2020 - 01/2002
4Therapeutics
09/2021 - 01/2016
2Implantable Defibrillators (Implantable Cardioverter-Defibrillator)
06/2008 - 01/2008
1Bariatric Surgery
01/2020